Liverpool manager Andoni Iraola confirms Alexander Isak and Cody Gakpo miss the Premier League match.

Liverpool striker Alexander Isak is a major doubt and will miss this weekend's crucial Premier League clash against Manchester City at Anfield, according to information published by FF2 Futebol.

The announcement comes at a delicate time as Manchester City returns to domestic action following an independent commission's verdict regarding financial rules, leaving Liverpool fans sweating over team selection.

Manager Andoni Iraola delivered the bad news during his pre-imatch press conference, confirming that both Isak and Cody Gakpo suffered injuries during the recent international break and are not ready to play.

Alexander Isak thigh injury timeline

The former Bournemouth manager explained that Isak picked up a knock to his thigh while away on international duty. Andoni Iraola noted that as a club manager, you are always waiting until the games end and hoping the doctor does not call with bad news.

The Swedish striker has unfortunately picked up over a dozen injuries since moving to English football. Andoni Iraola added that the current thigh issue does not look like a long-term problem, with the medical staff analyzing the situation on a day-to-day basis.

Cody Gakpo ankle issue adds to problems

Adding to the selection headache for Liverpool, Cody Gakpo also returned from international duty with an ankle injury. Andoni Iraola confirmed that both forwards are definitely not going to be involved in Sunday's match against the Citizens.

With Hugo Ekitike already sidelined with a long-term injury, the Basque coach may have to resort to using Bradley Barcola as a striker, or throw in Jason Koumas up top to lead the forward line.

Jeremy Jacquet and Federico Chiesa fitness updates

Amid the injury crisis, there is some positive news for the Anfield faithful regarding defender Jeremy Jacquet. The player has been exceptional since arriving in the summer and is fit and ready to go after international duty.

Andoni Iraola explained that Jeremy Jacquet did not play the last game with the national team purely as a measure of protection. Meanwhile, Italian winger Federico Chiesa is back in training ahead of the weekend fixture.

Frequently Asked Questions

Is Alexander Isak fit for Liverpool vs Manchester City?

No, Alexander Isak is not fit and has been officially ruled out of the upcoming Premier League match against Manchester City by manager Andoni Iraola due to a thigh injury.What injuries do Alexander Isak and Cody Gakpo have?

Alexander Isak picked up a knock to his thigh, while Cody Gakpo suffered an ankle injury during their respective time away on international duty with their national teams.

Who could replace Alexander Isak in the Liverpool lineup?

With Alexander Isak, Cody Gakpo, and Hugo Ekitike unavailable, Andoni Iraola may have to use Bradley Barcola or Jason Koumas as a striker against Manchester City.

When is the Liverpool vs Manchester City Premier League match?

The high-profile Premier League clash between Liverpool and Manchester City takes place this Sunday at Anfield as domestic action resumes following the international break.